46th Rosenstiel Award to Susan Lindquist will celebrate her remarkable scientific legacy
By Lawrence Goodman
The 46th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research has been awarded to Susan Lindquist, who tragically passed away on October 27 at age 67. In honor of Lindquist’s remarkable career, a symposium will be held on March 22, 2017, at Brandeis University. Three of Lindquist’s former colleagues, Daniel Jarosz (Stanford University), Leah Cowen (University of Toronto) and Sandro Santagata (Harvard University) will speak about Lindquist’s far-ranging scientific legacy.
Susan Lindquist was Professor of Biology and a member of the Whitehead Institute at MIT and a Howard Hughes Medical Institute investigator. Her research focused on the mechanisms of protein folding and the severe consequences of protein misfolding that are manifest in cancer, neurodegeneration and infectious disease.
Lindquist’s early work focused on prions, proteins that can adopt alternative conformation and can induce a similar refolding of other copies of the same protein. Her work extended to understanding how protein “chaperones” guide proper protein folding and prevent misfolded proteins from aggregating.